Semaglutide price comparison
GLP-1 receptor agonist. Prices from 8 vendors, all normalized to price per mg so a 5 mg and a 20 mg vial can be compared fairly.
What the research says about Semaglutide
Evidence map →Several randomized controlled trials in humans, often summarized by meta-analyses.
- 5,726
- Papers
- 311
- RCTs
- 789
- Reg. trials
Approved as a prescription drug (Ozempic, Wegovy, Rybelsus). Approval covers those pharmaceutical products, not research-grade vials.
- Human clinical studies: 659
- Animal / lab only: 273
- Other (reviews, untagged): 4794
- Meta-analyses / systematic reviews: 659
- Meta-analysisEfficacy and Safety of Semaglutide for Weight Loss in Obesity Without Diabetes: A Systematic Review and Meta-Analysis — Journal of the ASEAN Federation of Endocrine Societies, 2022
- Systematic reviewSubcutaneously administered tirzepatide vs semaglutide for adults with type 2 diabetes: a systematic review and network meta-analysis of randomised controlled trials — Diabetologia, 2024
- Randomized trialOral Semaglutide and Cardiovascular Outcomes in People With Type 2 Diabetes, According to SGLT2i Use: Prespecified Analyses of the SOUL Randomized Trial — Circulation, 2025
- Randomized trialOnce-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis — The New England journal of medicine, 2024
- Randomized trialSemaglutide and Cardiovascular Outcomes in Obesity without Diabetes — The New England journal of medicine, 2023
- Randomized trialWeight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension — Diabetes, obesity & metabolism, 2022
- Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema — recruiting · phase3
- A Study to Test Whether Different Doses of BI 456906 Are Effective in Treating Adults With Type 2 Diabetes. — completed · phase2
- Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists — completed · phase2
- Semaglutide as an Adjunct to Dieting in the Treatment of Type 2 Diabetes — unknown · phase4
- A Study to Evaluate Safety of Exposure to Wegovy During Pregnancy — enrolling by invitation
The grade reflects how much and what kind of research exists — not whether Semaglutide works or is safe. It is computed from PubMed study-type tags and ClinicalTrials.gov registrations as of Oct 22, 2026. Research use only; not medical advice.
Research & Pharmacokinetic Specs
Selective GLP-1 receptor agonist acylated with a C-18 fatty diacid chain, enhancing albumin binding and conferring DPP-4 resistance; slows gastric emptying and stimulates glucose-dependent insulin secretion.
Glucagon-like peptide-1 receptor (GLP-1R)
- •GI adverse effects (nausea, vomiting, diarrhea, constipation) very common during initiation
- •Risk of pancreatitis and gallbladder disease
- •Boxed warning for thyroid C-cell tumors in rodent bioassays
Cheapest Semaglutide by vial size
The lowest price at each size, across all vendors. Tap a size for the full ranking.
Where every vendor sits
Each dot is a vendor’s cheapest in-stock Semaglutide vial, in $ per mg. The spread between the leftmost dot and the median is what shopping around is worth.
Compare every Semaglutide offer
| Product | Size | Link to vendor | |||
|---|---|---|---|---|---|
| Bio Pepz United States SEMAGLUTIDE 10MG TESTED 81% · 4 | SEMAGLUTIDE 10MG | 10 mg vial | $35.20 | $3.52best | View ↗ |
| Trusted Peptide United States Semaglutide 10mg TESTED 80% · 2 | Semaglutide 10mg | 10 mg vial | $49.00 | $4.90 | View ↗ |
| Drexa Labs United States Semaglutide — 10mg COA CLAIMED | Semaglutide — 10mg | 10 mg vial | $50.00 | $5.00 | View ↗ |
| Bio Pepz United States SEMAGLUTIDE 5MG TESTED 81% · 4 | SEMAGLUTIDE 5MG | 5 mg vial | $26.40 | $5.28 | View ↗ |
| PSPeptides United States GLP-1 Semaglutide (1 Vial) — 10MG COA CLAIMED | GLP-1 Semaglutide (1 Vial) — 10MG | 10 mg vial | $64.99 | $6.50 | View ↗ |
| Polaris Peptides United States Semaglutide 20mg NO COA FOUNDTESTED 64% · 107 | Semaglutide 20mg | 20 mg vial | $165.00 | $8.25 | View ↗ |
| Umbrella Labs United States SEMAGLUTIDE PEPTIDE VIAL — 30mg Peptide Vial COA CLAIMED | SEMAGLUTIDE PEPTIDE VIAL — 30mg Peptide Vial | 30 mg vial | $249.99 | $8.33 | View ↗ |
| Polaris Peptides United States Semaglutide 12.5mg NO COA FOUNDTESTED 64% · 107 | Semaglutide 12.5mg | 12.5 mg vial | $105.00 | $8.40 | View ↗ |
| Polaris Peptides United States Semaglutide 10mg NO COA FOUNDTESTED 64% · 107 | Semaglutide 10mg | 10 mg vial | $90.00 | $9.00 | View ↗ |
| FRO Peptides United States Semaglutide – Research Peptide (5mg, 10mg) — 10mg COA CLAIMED | Semaglutide – Research Peptide (5mg, 10mg) — 10mg | 10 mg vial | $99.99 | $10.00 | View ↗ |
| Polaris Peptides United States Semaglutide 5mg NO COA FOUNDTESTED 64% · 107 | Semaglutide 5mg | 5 mg vial | $50.00 | $10.00 | View ↗ |
| Umbrella Labs United States SEMAGLUTIDE PEPTIDE VIAL — 20mg Peptide Vial COA CLAIMED | SEMAGLUTIDE PEPTIDE VIAL — 20mg Peptide Vial | 20 mg vial | $225.99 | $11.30 | View ↗ |
| Umbrella Labs United States SEMAGLUTIDE PEPTIDE VIAL — 15mg Peptide Vial COA CLAIMED | SEMAGLUTIDE PEPTIDE VIAL — 15mg Peptide Vial | 15 mg vial | $199.99 | $13.33 | View ↗ |
| FRO Peptides United States Semaglutide – Research Peptide (5mg, 10mg) — 5mg COA CLAIMED | Semaglutide – Research Peptide (5mg, 10mg) — 5mg | 5 mg vial | $69.99 | $14.00 | View ↗ |
| Polaris Peptides United States Semaglutide 2mg NO COA FOUNDTESTED 64% · 107 | Semaglutide 2mg | 2 mg vial | $30.00 | $15.00 | View ↗ |
| Umbrella Labs United States SEMAGLUTIDE PEPTIDE VIAL — 10mg Peptide Vial COA CLAIMED | SEMAGLUTIDE PEPTIDE VIAL — 10mg Peptide Vial | 10 mg vial | $179.99 | $18.00 | View ↗ |
| Umbrella Labs United States SEMAGLUTIDE PEPTIDE VIAL — 5mg Peptide Vial COA CLAIMED | SEMAGLUTIDE PEPTIDE VIAL — 5mg Peptide Vial | 5 mg vial | $99.99 | $20.00 | View ↗ |
| Nootropic Source United States Semaglutide (GLP-1 Analogue) 6mg COA CLAIMED | Semaglutide (GLP-1 Analogue) 6mg | 6 mg vial | $160.00 | $26.67 | View ↗ |
| Nootropic Source United States Semaglutide (GLP-1 Analogue) 3mg COA CLAIMED | Semaglutide (GLP-1 Analogue) 3mg | 3 mg vial | $90.00 | $30.00 | View ↗ |
| Umbrella Labs United States SEMAGLUTIDE PEPTIDE VIAL — 2mg Peptide Vial COA CLAIMED | SEMAGLUTIDE PEPTIDE VIAL — 2mg Peptide Vial | 2 mg vial | $65.99 | $32.99 | View ↗ |
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Semaglutide pricing FAQ
What is the cheapest Semaglutide right now?
Bio Pepz currently lists Semaglutide at $3.52 per mg (SEMAGLUTIDE 10MG, $35.20), the lowest of the 8 vendors we compare. The median is $8.25 per mg, so shopping around can save a lot.
How much does Semaglutide cost per mg?
Across 8 vendors, injectable Semaglutide ranges from $3.52 to $26.67 per mg, with a median of $8.25. Larger vials generally cost less per mg, which is why we normalize every listing to a price per milligram.
How much does a 10 mg vial of Semaglutide cost?
A 10 mg vial of Semaglutide costs between $35.20 and $179.99 across 7 vendors, with a median of $64.99. The cheapest is Bio Pepz at $35.20.
Which Semaglutide vendors publish a COA?
10 of the 16 vendors listing Semaglutide say they publish certificates of analysis (COAs). A COA is the vendor’s own claim and can be copied or re-dated, so we also show independent test ratings (Finnrick) on each vendor page where they exist, and let you filter to “COA claimed” vendors.
Does Semaglutide come in forms other than injectable vials?
We also track tablets listings for Semaglutide. They are priced per mg of active ingredient too, but usually cost more per mg than lyophilized vials. Use the form filter above to compare them.
Is there human research on Semaglutide?
PubMed lists 5,726 papers on Semaglutide: 311 randomized controlled trials, 659 human clinical studies and 273 animal or lab-only studies, plus 789 registered clinical trials. We grade the evidence base as “Strong”: Several randomized controlled trials in humans, often summarized by meta-analyses. This describes how much research exists, not whether it works.
Is Semaglutide legal and safe to use?
Semaglutide is sold for laboratory research use only. PeptideComps compares prices and does not give medical advice, and we can’t vouch for any product’s quality or legality — check the rules where you live.