Skip to content
PeptideComps logoPeptideComps
Metabolic

Retatrutide price comparison

Triple GIP / GLP-1 / glucagon receptor agonist. Prices from 9 vendors, all normalized to price per mg so a 5 mg and a 20 mg vial can be compared fairly.

ShareXRedditWhatsApp
Lowest price right now
$1.76
per mg · Bio Pepz
74% below the median
Compare all 81 offers ↓

What the research says about Retatrutide

Evidence map →
Evidence base
StrongMultiple human RCTs

Several randomized controlled trials in humans, often summarized by meta-analyses.

207
Papers
10
RCTs
33
Reg. trials

Investigational: in late-stage clinical trials, not approved anywhere.

Where the research comes from
  • Human clinical studies: 13
  • Animal / lab only: 10
  • Other (reviews, untagged): 184
  • Meta-analyses / systematic reviews: 36
Key studies
  1. Systematic reviewComparative effects of drugs for adults with overweight or obesity: systematic review and network meta-analysis — BMJ (Clinical research ed.), 2026
  2. Systematic reviewEfficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss Among Adults Without Diabetes : A Systematic Review of Randomized Controlled Trials — Annals of internal medicine, 2025
  3. Systematic reviewEmerging pharmacotherapies for obesity: A systematic review — Pharmacological reviews, 2025
  4. Randomized trialEfficacy and safety of retatrutide, a GIP, GLP-1, and glucagon receptor agonist, in people with type 2 diabetes and inadequate glycaemic control with diet and exercise (TRANSCEND-T2D-1): a double-blind, randomised, phase 3 trial — Lancet (London, England), 2026
  5. Randomized trialEffects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial — The lancet. Diabetes & endocrinology, 2025
  6. Randomized trialTriple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial — Nature medicine, 2024
All 207 papers on PubMed ↗

The grade reflects how much and what kind of research exists — not whether Retatrutide works or is safe. It is computed from PubMed study-type tags and ClinicalTrials.gov registrations as of Oct 22, 2026. Research use only; not medical advice.

Compound Knowledge Base

Research & Pharmacokinetic Specs

Phase 3 clinical trials (TRIUMPH program) for obesity, diabetes, and MASH
Mechanism of Action

Triple agonist at GIP, GLP-1, and Glucagon (GCGR) receptors. Glucagon agonism increases energy expenditure and hepatic fat oxidation while GIP/GLP-1 agonism controls appetite and glucose.

Target Receptors & Pathways

GIPR, GLP-1R, and Glucagon Receptor (GCGR)

Half-Life
~140 hours (~6 days)
Storage & Handling
Dry vials at -20°C. Reconstituted peptide refrigerated at 2–8°C; use within 30 days.
Scientific & Risk Flags
  • •Investigational only — Phase 3 ongoing; long-term clinical safety profile still being established
  • •Transient increases in resting heart rate and arrhythmia signals in early trials
  • •Gastrointestinal adverse events similar to dual agonists

Cheapest Retatrutide by vial size

The lowest price at each size, across all vendors. Tap a size for the full ranking.

Where every vendor sits

Each dot is a vendor’s cheapest in-stock Retatrutide vial, in $ per mg. The spread between the leftmost dot and the median is what shopping around is worth.

median $6.67Bio Pepz: $1.76PSPeptides: $3.83Drexa Labs: $4.79FRO Peptides: $6.67Polaris Peptides: $6.67Research Ready Peptides: $6.90Trusted Peptide: $7.20Prime Lab Peptides: $8.13NextChems: $8.66$1.76 cheapest$8.66

Compare every Retatrutide offer

Form
Size
Best $/mg
$1.76
Bio Pepz
Lowest price
$35.20
Bio Pepz · 5 mg vial
Median $/mg
$6.67
37 offers match
SizeLink to vendor
Bio Pepz
United States
Reta 100mg
TESTED 81% · 4
100 mg vial$176.00$1.76bestView ↗
Bio Pepz
United States
RETA 60MG
TESTED 81% · 4
60 mg vial$114.40$1.91View ↗
Bio Pepz
United States
RETA 50MG
TESTED 81% · 4
50 mg vial$105.60$2.11View ↗
Bio Pepz
United States
RETA 40mg
TESTED 81% · 4
40 mg vial$96.80$2.42View ↗
Bio Pepz
United States
RETA 30mg
TESTED 81% · 4
30 mg vial$79.20$2.64View ↗
Bio Pepz
United States
RETA 15mg
TESTED 81% · 4
15 mg vial$52.80$3.52View ↗
PSPeptides
United States
Retatrutide (1 Vial) — 60MG
COA CLAIMED
60 mg vial$229.99$3.83View ↗
PSPeptides
United States
Retatrutide (1 Vial) — 50MG
COA CLAIMED
50 mg vial$199.99$4.00View ↗
PSPeptides
United States
Retatrutide (1 Vial) — 40MG
COA CLAIMED
40 mg vial$164.99$4.12View ↗
Drexa Labs
United States
Retatrutide Research Peptide (Reta, LY3437943) — 100mg
COA CLAIMED
100 mg vial$479.00$4.79View ↗
PSPeptides
United States
Retatrutide (1 Vial) — 30MG
COA CLAIMED
30 mg vial$144.99$4.83View ↗
Drexa Labs
United States
Retatrutide Research Peptide (Reta, LY3437943) — 60mg
COA CLAIMED
60 mg vial$299.00$4.98View ↗
PSPeptides
United States
Retatrutide (1 Vial) — 20MG
COA CLAIMED
20 mg vial$104.99$5.25View ↗
Drexa Labs
United States
Retatrutide Research Peptide (Reta, LY3437943) — 30mg
COA CLAIMED
30 mg vial$169.00$5.63View ↗
Drexa Labs
United States
Retatrutide Research Peptide (Reta, LY3437943) — 20mg
COA CLAIMED
20 mg vial$119.00$5.95View ↗
PSPeptides
United States
Retatrutide (1 Vial) — 15MG
COA CLAIMED
15 mg vial$89.99$6.00View ↗
Drexa Labs
United States
Retatrutide Research Peptide (Reta, LY3437943) — 10mg
COA CLAIMED
10 mg vial$65.00$6.50View ↗
FRO Peptides
United States
Retatrutide – Research Peptide (10mg, 30mg) — 30mg
COA CLAIMED
30 mg vial$199.99$6.67View ↗
Polaris Peptides
United States
Retatrutide 60mg
NO COA FOUNDTESTED 64% · 107
60 mg vial$400.00$6.67View ↗
Research Ready Peptides
Canada
Retatrutide 40mg
COA CLAIMED
40 mg vial$275.99$6.90View ↗
Bio Pepz
United States
RETA 5MG
TESTED 81% · 4
5 mg vial$35.20$7.04View ↗
Trusted Peptide
United States
Retatrutide 10mg
TESTED 80% · 2
10 mg vial$72.00$7.20View ↗
PSPeptides
United States
Retatrutide (1 Vial) — 10MG
COA CLAIMED
10 mg vial$74.99$7.50View ↗
Research Ready Peptides
Canada
Retatrutide 15 mg
COA CLAIMED
15 mg vial$115.99$7.73View ↗
Polaris Peptides
United States
Retatrutide 35mg
NO COA FOUNDTESTED 64% · 107
35 mg vial$275.00$7.86View ↗
PSPeptides
United States
Retatrutide (1 Vial) — 5MG
COA CLAIMED
5 mg vial$39.99$8.00View ↗
Prime Lab Peptides
United States
Retatrutide – 24mg
COA CLAIMED
24 mg vial$195.00$8.13View ↗
NextChems
United States
Retatrutide — 30mg (1vial)
COA CLAIMED
30 mg vial$259.95$8.66View ↗
Polaris Peptides
United States
Retatrutide 15mg
NO COA FOUNDTESTED 64% · 107
15 mg vial$130.00$8.67View ↗
Polaris Peptides
United States
Retatrutide 10mg
NO COA FOUNDTESTED 64% · 107
10 mg vial$89.00$8.90View ↗
FRO Peptides
United States
Retatrutide – Research Peptide (10mg, 30mg) — 10mg
COA CLAIMED
10 mg vial$89.99$9.00View ↗
Polaris Peptides
United States
Retatrutide 5mg
NO COA FOUNDTESTED 64% · 107
5 mg vial$50.00$10.00View ↗
NextChems
United States
Retatrutide — 20mg (1vial)
COA CLAIMED
20 mg vial$215.94$10.80View ↗
Prime Lab Peptides
United States
Retatrutide – 12mg
COA CLAIMED
12 mg vial$150.00$12.50View ↗
NextChems
United States
Retatrutide — 10mg (1vial)
COA CLAIMED
10 mg vial$145.00$14.50View ↗
Prime Lab Peptides
United States
Retatrutide – 6mg
COA CLAIMED
6 mg vial$90.00$15.00View ↗
NextChems
United States
Retatrutide — 5mg (1vial)
COA CLAIMED
5 mg vial$120.00$24.00View ↗

Already bought Retatrutide?

Find out in 5 seconds whether you overpaid — and share your result.

Check my price →

Retatrutide pricing FAQ

What is the cheapest Retatrutide right now?

Bio Pepz currently lists Retatrutide at $1.76 per mg (Reta 100mg, $176.00), the lowest of the 9 vendors we compare. The median is $6.67 per mg, so shopping around can save a lot.

How much does Retatrutide cost per mg?

Across 9 vendors, injectable Retatrutide ranges from $1.76 to $8.66 per mg, with a median of $6.67. Larger vials generally cost less per mg, which is why we normalize every listing to a price per milligram.

How much does a 10 mg vial of Retatrutide cost?

A 10 mg vial of Retatrutide costs between $65.00 and $145.00 across 6 vendors, with a median of $89.00. The cheapest is Drexa Labs at $65.00.

Which Retatrutide vendors publish a COA?

10 of the 16 vendors listing Retatrutide say they publish certificates of analysis (COAs). A COA is the vendor’s own claim and can be copied or re-dated, so we also show independent test ratings (Finnrick) on each vendor page where they exist, and let you filter to “COA claimed” vendors.

Is there human research on Retatrutide?

PubMed lists 207 papers on Retatrutide: 10 randomized controlled trials, 13 human clinical studies and 10 animal or lab-only studies, plus 33 registered clinical trials. We grade the evidence base as “Strong”: Several randomized controlled trials in humans, often summarized by meta-analyses. This describes how much research exists, not whether it works.

Is Retatrutide legal and safe to use?

Retatrutide is sold for laboratory research use only. PeptideComps compares prices and does not give medical advice, and we can’t vouch for any product’s quality or legality — check the rules where you live.

More in Metabolic